AK Prof. Dr. D. Enders    
Deutsch Englisch
Institut für Organische Chemie

 

Ausgewählte Publikationen und Übersichtsartikel

  • D. Enders, in Asymmetric Synthesis Vol. 3, J.D. Morrison (Ed.), Academic Press, Orlando, 1984, 275 - 339, Alkylation of Chiral Hydrazones.
  • D. Enders, H. Kipphardt, P. Gerdes, L.J. Brena-Valle, V. Bushan, Bull.Soc.Chim. Belg. 1988, 97, 691 - 704. Large Scale Preparation of Versatile Chiral Auxiliaries Derived from (S)-Proline.
  • D. Enders in Stereoselective Synthesis, E. Ottow, K. Schöllkopf, B.-G. Schulz (Eds.), Springer-Verlag, Berlin, 1994, 63 - 90. Enzymemimetic C-C- and C-N-Bond Formations.
  • D. Enders, W. Bettray in Preceedings of the Chiral Europe '94 Symposium 1994, 51 - 60. Recent Advances in the Development of Highly Enantioselective Synthetic Methods.
  • D. Enders, Acros Organics Acta 1995, 1, 35 - 36. SADP and SAEP. Novel Chiral Hydrazine Auxiliaries for Asymmetric Synthesis.
  • D. Enders, Acros Organics Acta 1995, 1, 37 - 38. TMS-SAMP. Novel Chiral Hydrazine Auxiliary for Hetero-Michael Additions and Aza-Peterson Olefinations.
  • D. Enders, M. Klatt in Encyclopedia of Reagents for Organic Synthesis, L. A. Paquette, Ed., Wiley, New York, 1995, 3368 - 3370. (S)-2-Methoxymethylpyrrolidine.
  • D. Enders, M. Klatt in Encyclopedia of Reagents for Organic Synthesis, L. A. Paquette, Ed., Wiley, New York, 1995, 178 - 182. (S)-1-Amino-2-methoxymethylpyrrolidine.
  • D. Enders, B. Jandeleit, Acros Organics Acta 1995, 1,59- 60. (S,E)-(-)-Methyl-4-(phenylmethoxy)-2-pentenoate, a SyntheticallyUseful Enantiopure Building Block.
  • D. Enders, J. Kirchhoff, Acros Organics Acta 1996, 2, 10-11. (S,S)-(+)-2,2-Dimethyl-5-methylamino-4-phenyl-1,3-dioxan. Novel Chiral Auxiliary for Asymmetric Michael Additions.
  • D. Enders, W. Bettray, Pure Appl. Chem. 1996, 69, 569- 580. Recent Advances in the Development of Highly Enantioselective Synthetic Methods.
  • D. Enders, M. Klatt, Synthesis 1996, 1403 - 1421. Asymmetric Synthesis with (S)-2-Methoxymethylpyrrolidine (SMP) - a Pioneer Auxiliary.
  • D. Enders, W. Bettray, J. Schankat, J. Wiedemann in Enantioselective Synthesis of b-Amino Acids, E. Juaristi, Ed., VCH Verlag, Weinheim 1997, 187 - 210. Diastereo- and Enantioselective Synthesis of b -Amino Acids via SAMP Hydrazones and Hetero Michael Addition Using TMS-SAMP as a Chiral Equivalent of Ammonia.
  • D. Enders, U. Reinhold, Tetrahedron: Asymmetry 1997, 8,1895 - 1946. Asymmetric Synthesis of Amines by Nucleophilic 1,2-Addition of Organometallic Reagents to the CN-Double Bond.
  • D. Enders, J. Kirchhoff, P. Gerdes, D. Mannes, G. Raabe, J. Runsink, G. Boche, M. Marsch, H. Ahlbrecht, H. Sommer, Eur. J. Org. Chem. 1998,63 - 72. Structure and Reactivity of Lithiated a-Amino Nitriles.
  • S. Bräse, D. Enders, J. Köbberling, F. Avemaria, Angew. Chem. 1998, 110, 3614 - 3616; Angew. Chem. Int. Ed. Engl. 1998, 37, 3413 - 3415. Ein überraschender Festphaseneffekt: Entwicklung eines regenerierbaren "spurlosen" Linker-Systems für Festphasenreaktionen.
  • S. Bräse, J. Köbberling, D. Enders, R. Lazny, M. Wang, S. Brandtner, Tetrahedron Lett. 1999, 40, 2105 - 2108. Triazenes as Robust and Simple Linker for Amines in Solid-Phase Organic Synthesis.
  • D. Enders in " Horizonte - Die RWTH auf dem Weg ins 21. Jahrhundert", Springer Verlag, Berlin, 1999, S. 111. Asymmetrische Synthese spiegelbildlicher Moleküle.
  • D. Enders, K. Breuer, Comprehensive Asymmetric Catalysis, Vol. 3, E. N. Jacobsen, A. Pfaltz, H. Yamamoto (Hrsg.), Springer Verlag, Berlin, 1999, 1093 - 1102. Addition of Acyl Carbanion Equivalents to Carbonyl Groups and Enones.
  • D. Enders, J. P. Shilvock, Chem. Soc. Rev. 2000, 29, 359 - 373. Some Recent Applications of a-Amino Nitrile Chemistry.
  • J. H. Kirchhoff, S. Bräse, D. Enders, J. Comb. Chem. 2001, 3, 71 -77. A Novel Hydrazine Linker Resin and its Application for the Solid-Phase Synthesis of a-Branched Primary Amines.
  • D. Enders, H. Gielen, J. Organomet. Chem. 2001, 617-618, 70 - 80. Synthesis of chiral triazolinylidene transition metal complexes and first application in asymmetric catalysis.
  • D. Enders, B. Jandeleit, S. von Berg, G. Raabe, J. Runsink, Organometallics 2001, 4312 - 4332. Iron Mediated Allylic Substitution Reactions with Chirality Transfer. Stereochemistry of the Formation of Diastereo- and Enantiomerically Enriched Olefinic and Allylic Tetracarbonyl Iron Complexes.
  • A. Job, C. F. Janeck, W. Bettray, R. Peters, D. Enders, Tetrahedron 2002, 58, 2253 - 2329. The SAMP/RAMP-Hydrazone Methodology in Asymmetric Synthesis.
  • D. Enders, M. Voith, A. Lenzen, Angew. Chem. 2005, 117; Angew. Chem. Int. Ed. 2005, 1330 – 1351; Angew. Chem. Int. Ed. 2005, 44, 1304 – 1325. The Dihydroxyacetone Unit - a Versatile C3-Building Block in Organic Synthesis.
  • D. Enders, C. Grondal, Angew. Chem. 2005, 117, 1235 – 1238. Angew. Chem. Int. Ed. 2005, 44, 1210 – 1212. Direkte organokatalytische de novo-Synthese von Kohlenhydraten.
  • D. Enders, M. Boudou, J. Gries in New Methods for the Asymmetric Synthesis of Nitrogen Heterocycles, J. L. Vicario, D. Badia, L. Carrillo (Eds.), Research Signpost, Trivandrum, India, 2005, 1 - 31. Asymmetric Syntheses of Four-, Five- and Six-Membered N-Heterocycles Employing the SAMP/RAMP-Hydrazone Methodology.
  • D. Enders, C. Grondal, M. Vrettou, G. Raabe, Angew. Chem. 2005, 117, 4147 – 4151; Angew. Chem. Int. Ed. 2005, 44, 4079 - 4083. Asymmetrische Synthese von selektiv geschützten Aminozucker-Derivaten via direkte organokatalytische Mannich-Reaktion.
  • D. Enders, A. Saint-Dizier, M. I. Lannou, A. Lenzen, Eur. J. Org. Chem. 2006, 29 - 49. The Phospha-Michael Addition in Organic Synthesis.
  • D. Enders, W. Bettray in Asymmetric Synthesis – The Essentials, S. Bräse, M. Christmann, Eds., Wiley-VCH, Weinheim, 2006, Asymmetric Syntheses with SAMP-/RAMP-Hydrazones.
  • D. Enders, T. Balensiefer, O. Niemeier, M. Christmann in Enantioselective Organocatalysis, Reactions and Experimental Procedures, P. Dalko, Ed., Wiley-VCH, Weinheim, 2006,  Nucleophilic N-Heterocyclic Carbenes in Asymmetric Organocatalysis.
  • D. Enders, M. R. M. Hüttl, C. Grondal, G. Raabe, Nature 2006, 441, 861 - 863. Asymmetric Organocatalytic Domino Reactions. Control of Four Stereocentres in a Triple Cascade.
  • D. Enders, W. Bettray in Asymmetric Synthesis with Chemical and Biological Methods, D. Enders, K.-E. Jaeger, Eds., Wiley-VCH, Weinheim, 2007, 1 - 37. Development of Novel Enantioselective Synthetic Methods.
  • D. Enders, W. Bettray in Asymmetric Synthesis with Chemical and Biological Methods, D. Enders, K.-E. Jaeger, Eds., Wiley-VCH, Weinheim, 2007, 38 - 75. Asymmetric Synthesis of Natural Products Employing the SAMP/RAMP-Hydrazone Methodology.
  • D. Enders, O. Niemeier, A. Henseler, Chem. Rev. 2007, 107, 5605 - 5655. Organocatalysis by N-Heterocyclic Carbenes.
  • R. Brehme, D. Enders, R. Fernandez, J. M. Lassaletta, Eur. J. Org. Chem. 2007, 5629 - 5660. Aldehyde N,N-Dialkylhydrazones as Neutral Acyl Anion Equivalents. Umpolung of the Imine Reactivity.
  • D. Enders, C. Grondal, M. R. M. Hüttl, Angew. Chem. 2007, 119, 1590 - 1601; Angew. Chem. Int. Ed. 2007, 46, 1570 - 1581. Asymmetric Organocatalytic Domino Reactions.
  • D. Enders, K. Lüttgen, A. A. Narine, Synthesis 2007, 959 - 980. Asymmetric Sulfa-Michael Additions.
  • D. Enders, M. R. M. Hüttl, O. Niemeier, Organocatalysis, M. T. Reetz, B. List, S. Jaroch, H. Weinmann (Eds.), Springer-Verlag, Berlin, 2008, 45 - 124. Biomimetic Organocatalytic C-C-Bond Formations.
  • D. Enders, M. R. M. Hüttl. G. Raabe, J. W. Bats, Adv. Synth. Cat. 2008, 350, 267 - 279. Asymmetric Synthesis of Polyfunctionalized
    Mono-, Bi-, and Tricyclic Carbon Frameworks via Organocatalytic Domino Reactions
    .
  • D. Enders, A. A. Narine, F. Toulgoat, T. Bisschops, Angew. Chem. 2008, 120, 5744-5748. Angew. Chem. Int. Ed. 2008, 47, 5661-5665. Asymmetric Brønsted Acid-Catalyzed Isoindoline Synthesis: Enhancement of Enantiomeric Ratio by Stereoablative Kinetic Resolution.
  • D. Enders, C. Wang, J. W. Bats, Angew. Chem. 2008, 120, 7649 - 7653; Angew. Chem. Int. Ed. 2008, 47, 7539 - 7542. Organocatalytic Asymmetric Domino Reactions: A Cascade Consisting of a Michael Addition and an Aldehyde a-Alkylation.
  • D. Enders, A. A. Narine, J. Org. Chem. 2008, 73, 7857 - 7870. Lessons from Nature: Biomimetic Organocatalytic Carbon-Carbon Bond Formations.
  • D. Enders, C. Wang, J. W. Bats, Synlett 2009, 1777-1780. Asymmetric Synthesis of Functionalized 3,4-Dihydronaphthalenes via an Organocatalytic Domino Nitroalkane-Michael/Aldol Condensation Reaction.
  • D. Enders, A. Henseler, Adv. Synth. Catal. 2009, 351, 1749-1752. A Direct Intermolecular Cross-Benzoin Type Reaction: N-Heterocyclic Carbene Catalyzed Coupling of Aromatic Aldehydes with Trifluoromethyl Ketones.
  • D. Enders, C. Wang, G. Raabe, Synthesis. 2009, 4119-4124. Enantioselective Synthesis of 3H-Pyrrolo[1,2-a]indole-2-carbaldehydes via an Organocatalytic Domino aza-Michael/Aldol Condensation Reaction.
  • D. Enders, C. Wang, J. X. Liebich, Chem. Eur. J. 2009, 15, 11058 - 11076. Asymmetric Organocatalytic Aza-Michael Additions.
  • D. Enders, R. Krüll, W. Bettray, Synthesis 2010, 567 - 572. Microwave Assisted Organocatalytic Quadruple Domino Reactions of Acetaldehyde and Nitroalkenes.
  • C. Grondal, M. Jeanty, D. Enders, Nature Chemistry 2010, 2, 167 - 178. Organocatalytic Cascade Reactions as a New Tool in Total Synthesis.
  • D. Enders, C. Wang, M. Mukanova, A. Greb, Chem. Commun. 2010, 46, 2447 - 2449. Organocatalytic Asymmetric Synthesis of Polyfunctionalized 3-(Cyclohexenyl-methyl)-indoles via a Quadruple Domino Friedel-Crafts-type / Michael/Michael/ Aldol Condensation Reaction.
  • D. Enders, A. Grossmann, J. Fronert, G. Raabe, Chem. Commun. 2010, 46, 6282 -6284. N-Heterocyclic Carbene Catalysed Asymmetric Cross-Benzoin Reactions of Heteroaromatic Aldehydes with Trifluoromethyl Ketones.
  • D. Enders, A. Grossmann, H. Huang, G. Raabe, Eur. J.Org. Chem.  2011, 4298 - 4301. Dual Secondary Amine/N-Heterocyclic Carbene Catalysis in the Asymmetric Michael ­- Cross-Benzoin Cascade Reaction of ß-Ketosulfones with Enals.
  • C. C. J. Loh, J. Badorrek, G. Raabe, D. Enders, Chem. Eur. J. 2011, 17, 13408 - 13414. Merging Organocatalysis and Gold Catalysis: Enantioselective Synthesis of Tetracyclic Indol Derivatives via a Sequential Double Friedel-Crafts-Type Reaction.
  • A. Grossmann, D. Enders, Angew. Chem. 2012, 124, 320 – 332; Angew. Chem. Int. Ed. 2012, 51, 314 - 325. N-Heterocyclic Carbene Catalyzed Domino Reactions.
  • C. C. J. Loh, D. Enders, Chem. Eur. J. 2012, 18, 10212 - 10225. Merging Organocatalysis and Gold Catalysis – A Critical Evaluation of the Underlying Concepts.
  • S. Takizawa, T. M.-N. Nguyen, A. Grossmann, D. Enders, H. Sasai, Angew. Chem. 2012, 124, 5519 - 5522; Angew. Chem. Int. Ed.
    2012, 51, 5423 - 5426. Enantioselective Synthesis of a-Alkylidene-g-butyrolactones via Intramolecular Rauhut-Currier Reaction Promoted by Acid-Base Organocatalysts.
  • D. Enders, A. Greb, K. Deckers, P. Selig, C. Merkens, Chem. Eur. J. 2012, 18, 10226 - 10229. Quadruple Domino Organocatalysis: An Asymmetric aza-Michael/Michael/Michael/Aldol Reaction Sequence Leading to Tetracyclic Indole Structures with Six Stereocenters.
  • V. Nguyen, D. Enders, Org. Biomol. Chem. 2012, 10, 5327 - 5331. Chiral Quaternary Phosphonium Salts: A New Class of Organocatalysts.
  • T. V. Nguyen, J. Hartmann, D. Enders, Synthesis 2013, 45, 845 - 873. Recent Synthetic Strategies to Access Seven-Membered Carbocycles in Natural Product Synthesis.
  • X. Zeng, Q. Ni, G. Raabe, D. Enders, Angew. Chem2013, 125, 3050 – 3054; Angew. Chem. Int. Ed. 2013, 52, 2977 - 2980. A Branched Domino Reaction: Two Component Quadruple Organocatalytic Asymmetric Synthesis of Polyfunctionalized Cyclohexene Derivatives.
  • N. Erdmann, A. R. Philipps, I. Atodiresei, D. Enders, Adv. Synth. Catal. 2013, 355, 847 - 857. An Asymmetric Organocatalytic Quadruple Cascade Initiated by a Friedel-Crafts-Type Reaction with Electron-Rich Arenes.
  • C. C. J. Loh, I. Atodiresei, D. Enders, Chem. Eur. J. 2013, 19, 10822 - 10826. Asymmetric Organocatalytic Michael/Henry Domino Reactions through Hydrogen Bonding Activation: A Kinetic Access into Indane Scaffolds Bearing cis-Vicinal Substituents.
  • P. Chauhan, D. Enders, Angew. Chem. 2014, 126, 1509 – 1511; Angew. Chem. Int. Ed. 2014, 53, 1485 - 1487. N-Heterocyclic Carbene Catalyzed Activation of Esters: A New Option for Asymmetric Domino Reactions.
  • P. Chauhan, G. Urbanietz, G. Raabe, D. Enders, Chem. Commun. 2014, 50, 6853 - 6855. Asymmetric Synthesis of Functionalised Cyclohexanes Bearing Five Stereocenters via a One-Pot Organocatalytic Michael/Michael/1,2-Addition Sequence.
  • P. Chauhan, S. Mahajan, C. C. J. Loh, G. Raabe, D. Enders, Org. Lett. 2014, 16, 2954 - 2957. Stereocontrolled Construction of Six Vicinal Stereogenic Centers on Spiropyrazolones via Organocascade Michael/Michael/1,2-Addition Reactions.
  • R. Hahn, G. Raabe, D. Enders, Org. Lett. 2014, 16, 3636 - 3639. Asymmetric Synthesis of Highly Functionalized Tetrahydropyrans via a One-Pot Organocatalytic Michael/Henry/Ketalization Sequence.
  • D. Hack, P. Chauhan, K. Deckers, G. N. Hermann, L. Mertens, G. Raabe, D. Enders, Org. Lett. 2014, 16, 5188 - 5191. Combining Silver- and Organocatalysis: A Sequential Michael-Addition/Hydroalkoxylation One-Pot Approach to Annulated Coumarins.
  • P. Chauhan, S. Mahajan, U. Kaya, D. Hack, D. Enders, Adv. Synth. Catal. 2015, 357, 253 –281. Bifunctional Amine-Squaramides: Powerful Hydrogen-Bonding Organocatalysts for Asymmetric Domino/Cascade Reactions.
  • P. Chauhan, S. Mahajan, G. Raabe, D. Enders, Chem. Commun. 2015, 51, 2270 - 2272. Organocatalytic One-Pot 1,4-/1,6-/1,2-Addition Sequence for the Stereocontrolled Formation of Six Consecutive Stereocenters.
  • K. Zhao, T. Shu, J.Jia, G. Raabe, D. Enders, Chem. Eur. J. 2015, 21, 3933 - 3936. An Organocatalytic Mannich/Denitration Reaction for the Asymmetric Synthesis of 3-Ethylacetate-Substitued 3-Amino-2-Oxindoles. Formal Synthesis of AG-041R.
  • C. Beceño, P. Chauhan, A. Rembiak, A. Wang, D. Enders, Adv. Synth. Catal. 2015, 357, 672 - 676. Brønsted Acid Catalyzed Enantioselective Synthesis of Isatin DerivedN,S-Acetals.
  • D. Hack, M. Blümel, P. Chauhan, A. Philipps, D. Enders, Chem. Soc. Rev. 2015, 44, 6059 - 6093. Catalytic Conia-Ene and Related Reactions.
  • P. Chauhan, S. Mahajan, D. Enders, Chem. Commun. 2015, 51, 12890 - 12907. Asymmetric Synthesis of Pyrazoles and Pyrazolones Employing the Reactivity of Pyrazolin-5-one Derivatives.
  • K. Zhao, Y. Zhi, A. Wang, D. Enders, ACS Catalysis 2016, 6, 657 - 660. Asymmetric Organocatalytic Synthesis of 3-Diarylmethine-Substituted Oxindoles Bearing a Quaternary Stereocenter via 1,6-Conjugate Addition to para-Quinone Methides.
  • T. Shu, Q. Ni, X. Song, K. Zhao, T. Wu, R. Puttreddy, K. Rissanen, D. Enders, Chem. Commun. 2016, 52, 2609 - 2611. Asymmetric Synthesis of Cyclopentanes Bearing Four Contiguous Stereocenters via an NHC-Catalyzed Michael/Michael/ Esterification Domino Reaction.
  • D. Hack, A. Dürr, K. Deckers, P. Chauhan, N. Seling, L. Rübenach, L. Mertens, G. Raabe, F. Schoenebeck, D. Enders, Angew. Chem. 2016, 128, 1829 - 1832; Angew. Chem. Int. Ed. 2016, 55, 1797 - 1800. Asymmetric Synthesis of Spiropyrazolones by Sequential Organo- and Silver Catalysis.
  • U. Kaya, P. Chauhan, D. Hack, K. Deckers, R. Puttreddy, K. Rissanen, D. Enders, Chem. Commun. 2016, 52, 1669 - 1672. Enantioselective Synthesis of 4H-Pyranonaphthochinones via a Sequential Squaramide and Silver Catalysis.
  • L. Wang, S. Li, M. Blümel, A. R. Philipps, A. Wang, R. Puttreddy, K. Rissanen, D. Enders, Angew. Chem. 2016, 128, 11276 – 11280; Angew. Chem. Int. Ed. 2016, 55, 11110 – 11114. Asymmetric Synthesis of Spirobenzazepinones with Atroposelectivity and Spiro-1,2-Diazepinones via NHC-Catalyzed [3+4] Annulation Reactions.
  • M. Blümel, R. D. Crocker, J. B. Harper, D. Enders, T. V. Nguyen, Chem. Commun. 2016, 52, 7958 - 7961. N-Heterocyclic Olefins as Efficient Phase-Transfer Catalysts for Base-Promoted Alkylation Reactions.
  • K. Zhao, Y. Zhi, T. Shu, A. Valkonen, K. Rissanen, D. Enders, Angew. Chem. 2016, 128, 12283 – 12287; Angew. Chem. Int. Ed. 2016, 55, 12107 - 12108. Organocatalytic Domino Oxa-Michael/1,6- Addition Reactions: A Strategy for the Asymmetric Synthesis of Chromans Bearing Oxindole Scaffolds.
  • S. Dochain, F. Vetica, R. Puttreddy, K. Rissanen, Angew. Chem. 2016, 128, 16387 -16389; Angew. Chem. Int. Ed. 2016, 55, 16153 - 16155. Combining Organocatalysisand Lanthanide Catalysis: A Sequential One-Pot Quadruple Domino/Diels-AlderAsymmetric Synthesis of Functionalized Tricycles.
  • K. Zhao, D. Enders, Angew. Chemie 2017, accepted. Merging N-Heterocyclic Carbene Catalysis and Single Electron Transfer: A New Strategy for Asymmetric Transformations.
  • F. Vetica, P. Chauhan, S. Dochain, D. Enders, Chem. Soc. Rev. 2017, DOI:10.1039/c6cs00757k. Asymmetric Organocatalytic Methods for the Synthesis of Tetrahydropyrans and Their Application in Total Synthesis.
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    letzte Aktualisierung 08.03.2017